#151612

Anti-ATG13 [ATG13]

Cat. #151612

Anti-ATG13 [ATG13]

Cat. #: 151612

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 10-12 weeks

Target: ATG13

Class: Polyclonal

Application: WB

Reactivity: Human

Host: Rabbit

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Sharon Tooze

Institute: Cancer Research UK, London Research Institute: Lincoln's Inn Fields

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Anti-ATG13 [ATG13]
  • Clone: ATG13
  • Tool sub type: Primary antibody
  • Class: Polyclonal
  • Conjugation: Unconjugated
  • Reactivity: Human
  • Host: Rabbit
  • Application: WB
  • Description: Atg13 only binds in the unphosphorylated state, and its dephosphorylation has been shown to be TOR dependent.
  • Immunogen: C-terminal synthetic peptide

Target Details

  • Target: ATG13
  • Target background: Autophagy has been implicated in a number of medical contexts, such as cancer, neurodegeneration, and immunity. The serine-threonine protein kinase Atg1 was originally identified as a critical autophagy regulator in yeast. Full kinase activity of Atg1 in yeast requires its binding partners Atg13 and Atg17.

Applications

  • Application: WB

Handling

  • Format: Liquid
  • Unit size: 100 ug
  • Shipping conditions: Shipping at 4° C

References

  • Chan et al. 2009. Mol Cell Biol. 29(1):157-71. PMID: 18936157.
  • Kinase-inactivated ULK proteins inhibit autophagy via their conserved C-terminal domains using an Atg13-independent mechanism.