#151586

Anti-WSTF [WSTF]

Cat. #151586

Anti-WSTF [WSTF]

Cat. #: 151586

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 10-12 weeks

Target: Williams Syndrome Transcription Factor (WSTF)

Class: Polyclonal

Application: IF ; IP ; WB

Reactivity: Human ; Mouse

Host: Rabbit

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Patrick Varga-Weisz

Institute: Marie Curie Research Institute

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Anti-WSTF [WSTF]
  • Clone: WSTF
  • Tool sub type: Primary antibody
  • Class: Polyclonal
  • Purpose: Marker
  • Conjugation: Unconjugated
  • Molecular weight: 170 kDa
  • Reactivity: Human ; Mouse
  • Host: Rabbit
  • Application: IF ; IP ; WB
  • Description: The human Williams Syndrome Transcription Factor (WSTF) gene is located within the common Williams Syndrome deletion area at chromosome 7q11.23. Its functional motifs include a PHD zinc finger motif followed by a bromodomain. Both motifs are found in many transcription factors, suggesting that WSTF may function as a transcription factor. WSTF forms a chromatinremodelling complex that mobilizes nucleosomes and reconfigures irregular chromatin to a regular nucleosomal array structure. The droso...
  • Immunogen: Peptide coupled to keyhole limpet hemocyanin.
  • Recommended controls: ES, NIH 3T3, and HeLa cells

Target Details

  • Target: Williams Syndrome Transcription Factor (WSTF)
  • Molecular weight: 170 kDa
  • Tissue cell line specificity: Sheep
  • Target background: The human Williams Syndrome Transcription Factor (WSTF) gene is located within the common Williams Syndrome deletion area at chromosome 7q11.23. Its Fn motifs include a PHD zinc finger motif followed by a bromodomain. Both motifs are found in many transcription factors, suggesting that WSTF may function as a transcription factor. WSTF forms a chromatinremodelling complex that mobilizes nucleosomes and reconfigures irregular chromatin to a regular nucleosomal array structure. The drosophila Ac...

Applications

  • Application: IF ; IP ; WB

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: Whole serum
  • Storage conditions: -80° C
  • Shipping conditions: Shipping at 4° C

References

  • Sarshad et al. 2013. PLoS Genet. 9(3):e1003397. PMID: 23555303.
  • Nuclear myosin 1c facilitates the chromatin modifications required to activate rRNA gene transcription and cell cycle progression.
  • Bozhenok et al. 2002. EMBO J. 21(9):2231-41. PMID: 11980720.
  • WSTF-ISWI chromatin remodeling complex targets heterochromatic replication foci.