Cat. #151584
Anti-SNF2H [SNF2H]
Cat. #: 151584
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 10-12 weeks
Target: SNF2H
Class: Polyclonal
Application: ChIP ; IHC ; IF ; IP ; WB
Reactivity: Human ; Mouse
Host: Rabbit
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Patrick Varga-Weisz
Institute: Marie Curie Research Institute
Tool Details
*FOR RESEARCH USE ONLY
- Name: Anti-SNF2H [SNF2H]
- Clone: SNF2H
- Tool sub type: Primary antibody
- Class: Polyclonal
- Conjugation: Unconjugated
- Molecular weight: 121 kDa
- Reactivity: Human ; Mouse
- Host: Rabbit
- Application: ChIP ; IHC ; IF ; IP ; WB
- Description: SNF2H is a human homolog of the budding yeast Snf2 protein, and is a member of the SWI/SNF family of proteins. The members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. SNF2H is the catalytic subunit of several chromatin remodelling complexes, such as CHRAC, RSF, ACF, NuRD and NoRC. SNF2H is similar in sequence to the Drosophila ISWI chromatin remodelling protein.
- Immunogen: Peptide coupled to keyhole limpet hemocyanin
Target Details
- Target: SNF2H
- Molecular weight: 121 kDa
- Target background: SNF2H is a human homolog of the budding yeast Snf2 protein, and is a member of the SWI/SNF family of proteins. The members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. SNF2H is the catalytic subunit of several chromatin remodelling complexes, such as CHRAC, RSF, ACF, NuRD and NoRC. SNF2H is similar in sequence to the Drosophila ISWI chromatin remodelling protein.
Applications
- Application: ChIP ; IHC ; IF ; IP ; WB
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Unit size: 100 ug
- Storage buffer: Whole serum
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- Mueller et al. 2013. Oncogene. 32(9):1164-72. PMID: 22525276.
- The miR-99 family regulates the DNA damage response through its target SNF2H.
- Sacilotto et al. 2011. PLoS One. 6(8):e23318. PMID: 21858068.
- Epigenetic transcriptional regulation of the growth arrest-specific gene 1 (Gas1) in hepatic cell proliferation at mononucleosomal resolution.
- Lessard et al. 2010. Mol Cell. 38(4):539-50. PMID: 20513429.
- The ARF tumor suppressor controls ribosome biogenesis by regulating the RNA polymerase I transcription factor TTF-I.
- Bozhenok et al. 2002. EMBO J. 21(9):2231-41. PMID: 11980720.
- WSTF-ISWI chromatin remodeling complex targets heterochromatic replication foci.
