#151535

Anti-APC11 [AX2.1]

Cat. #151535

Anti-APC11 [AX2.1]

Cat. #: 151535

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 1-2 weeks

Target: Anaphase Promoting Complex (APC) 11

Class: Monoclonal

Application: ELISA ; WB

Reactivity: Human ; Xenopus laevis

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Julian Gannon

Institute: Cancer Research UK, London Research Institute: Clare Hall Laboratories

Tool Details
Target Details
Applications
Handling

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Anti-APC11 [AX2.1]
  • Clone: AX2.1
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Strain: Balb/c
  • Reactivity: Human ; Xenopus laevis
  • Host: Mouse
  • Application: ELISA ; WB
  • Description: APC11 is the catalytic subunit of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. Specifically, Apc11 acts as an E3 enzyme and is responsible for recruiting E2s to the APC and for mediating the subsequent transfer of ubiquitin to APC substrates in vivo.
  • Immunogen: Peptide spanning carboxy region of APC11.
  • Isotype: IgG1
  • Myeloma used: Sp2/0-Ag14
  • Recommended controls: APC11 immunoprecipitated from Xenopus egg extract

Target Details

  • Target: Anaphase Promoting Complex (APC) 11
  • Tissue cell line specificity: APC11 immunoprecipitated from Xenopus egg extract
  • Target background: APC11 is the catalytic subunit of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. Specifically, Apc11 acts as an E3 enzyme and is responsible for recruiting E2s to the APC and for mediating the subsequent transfer of ubiquitin to APC substrates in vivo.

Applications

  • Application: ELISA ; WB

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C