Cat. #151430
Anti-FCER2 [BU38]
Cat. #: 151430
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 3-4 weeks
Target: Fc epsilon RII (FCER2, CD23)
Class: Monoclonal
Application: FACS ; IHC ; IF ; IP ; WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Institute: University of Birmingham
Tool Details
*FOR RESEARCH USE ONLY
- Name: Anti-FCER2 [BU38]
- Alternate name: Fc Fragment Of IgE Receptor II; Immunoglobulin E-Binding Factor; Lymphocyte IgE Receptor; Fc Epsilon Receptor II; CD23 Antigen; BLAST-2; CLEC4J; IGEBF; FCE2; C-Type Lectin Domain Family 4; Member; Immunoglobulin Epsilon-Chain; CD23
- Clone: BU38
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Reactivity: Human
- Host: Mouse
- Application: FACS ; IHC ; IF ; IP ; WB
- Description: Fc epsilon RII (CD23), a low-affinity IgE receptor, is widely expressed on the surface of a number of cell types. Fc epsilon RII mediates numerous IgE-related immune responses. Both membrane and soluble Fc epsilon RII play important roles in allergic responses.
- Immunogen: Full length native CD23 of human origin
- Isotype: IgG1
- Myeloma used: NS0
- Recommended controls: Follicular lymphoma or tonsil (mantle cell lymphomas are negative)
Target Details
- Target: Fc epsilon RII (FCER2, CD23)
- Tissue cell line specificity: Follicular lymphoma or tonsil (mantle cell lymphomas are negative)
- Target background: Fc epsilon RII (CD23), a low-affinity IgE receptor, is widely expressed on the surface of a number of cell types. Fc epsilon RII mediates numerous IgE-related immune responses. Both membrane and soluble Fc epsilon RII play important roles in allergic responses.
Applications
- Application: FACS ; IHC ; IF ; IP ; WB
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- Aubry JP. et al. 1987. Leucocyte Typing III. Oxford University Press-Oxford, New York, Tokyo
- Knapp W. et al. 1989. Leukocyte Typing IV. Oxford University Press
- Leucocyte Typing VI, Garland Publishing (1998)
- Schlossman S.F. et al. 1995. Leukocyte Typing V. Oxford University Press
- Maeda et al. 2002. J Histochem Cytochem. 50(11):1475-86. PMID: 12417613.
- Immunohistochemical recognition of human follicular dendritic cells (FDCs) in routinely processed paraffin sections.
- Karagiannis et al. 2001. Immunology. 103(3):319-31. PMID: 11454061.
- Endocytosis and recycling of the complex between CD23 and HLA-DR in human B cells.
- Sancho et al. 2000. J Immunol. 165(7):3868-75. PMID: 11034393.
- Fn analysis of ligand-binding and signal transduction domains of CD69 and CD23 C-type lectin leukocyte receptors.
- Chen et al. 2000. Appl Immunohistochem Mol Morphol. 8(1):1-11. PMID: 10937042.
- Classification of small B-cell lymphoid neoplasms using a paraffin section immunohistochemical panel.
- Sano et al. 1999. Proc Assoc Am Physicians. 111(1):82-91. PMID: 9893160.
- Upregulated surface expression of intracellularly sequestered Igepsilon receptors (FcepsilonRII/CD23) following activation in human peripheral blood eosinophils.
- Kroft et al. 1998. Mod Pathol. 11(10):967-70. PMID: 9796724.
- Evaluation of CD23 expression in paraffin-embedded gastric lymphomas of mucosa-associated lymphoid tissue.
- Sarsfield et al. 1996. J Pathol. 180(1):18-25. PMID: 8943810.
- Kumar et al. 1996. Mod Pathol. 9(9):925-9. PMID: 8878025.
- Use of CD23 (BU38) on paraffin sections in the diagnosis of small lymphocytic lymphoma and mantle cell lymphoma.
- A study of accessory cells in the acquired lymphoid tissue of helicobacter gastritis.
- Bonnefoy et al. 1995. Curr Opin Immunol. 7(3):355-9. PMID: 7546400.
- CD23 and B-cell activation.
- Hardie et al. 1993. Eur J Immunol. 23(5):997-1004. PMID: 8477815.
- Quantitative analysis of molecules which distinguish Fn compartments within germinal centers.
- Murray et al. 1991. J Pathol. 165(2):125-8. PMID: 1744798.
- CD23 expression in non-Hodgkin lymphoma: immunohistochemical demonstration using the antibody BU38 on paraffin sections.
- Hellen et al. 1991. J Clin Pathol. 44(4):293-6. PMID: 1827636.
- Immunohistochemical demonstration of CD23 expression on lymphocytes in rheumatoid synovitis.
- Rowlands et al. 1990. J Pathol. 160(3):239-43. PMID: 2139890.
- Immunohistochemical determination of CD23 expression in Hodgkin's disease using paraffin sections.
