#151377

Anti-LILR [GHI/75]

Cat. #151377

Anti-LILR [GHI/75]

Cat. #: 151377

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 1-2 weeks

Target: Leukocyte Immunogolobulin-like Receptor 1 (LILR, CD85)

Class: Monoclonal

Application: FACS ; IHC ; IF ; IP ; WB

Reactivity: Human

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Karen Pulford

Institute: University of Oxford

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Anti-LILR [GHI/75]
  • Clone: GHI/75
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Purpose: Marker
  • Conjugation: Unconjugated
  • Reactivity: Human
  • Host: Mouse
  • Application: FACS ; IHC ; IF ; IP ; WB
  • Description: LILR is a 120kD membrane glycoprotein expressed strongly on plasma cells, moderately on circulating B cells and weakly on monocytes. It is not expressed on neutrophils, T cells, NK cells or any non-hematopoietic cells.
  • Immunogen: Hairy cell leukaemia cells
  • Isotype: IgG2b
  • Myeloma used: P3/NS1/1-Ag4.1

Target Details

  • Target: Leukocyte Immunogolobulin-like Receptor 1 (LILR, CD85)
  • Tissue cell line specificity: Mouse
  • Target background: LILR is a 120kD membrane glycoprotein expressed strongly on plasma cells, moderately on circulating B cells and weakly on monocytes. It is not expressed on neutrophils, T cells, NK cells or any non-hematopoietic cells.

Applications

  • Application: FACS ; IHC ; IF ; IP ; WB

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C

References

  • Morel et al. 2008. J Immunol. 181(4):2368-81. PMID: 18684926.
  • HLA class I molecules regulate IFN-gamma production induced in NK cells by target cells, viral products, or immature dendritic cells through the inhibitory receptor ILT2/CD85j.
  • Kirwan et al. 2005. J Immunol. 175(8):5006-15. PMID: 16210603.
  • Killer cell Ig-like receptor-dependent signaling by Ig-like transcript 2 (ILT2/CD85j/LILRB1/LIR-1).
  • Banham et al. 1999. J Leukoc Biol. 65(6):841-5. PMID: 10380908.
  • Identification of the...