Cat. #151301
Anti-Plx [AZ44]
Cat. #: 151301
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 1-2 weeks
Target: Polo-like-kinase protein (Plk)
Class: Monoclonal
Application: WB ; ELISA ; WB
Reactivity: Xenopus laevis
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Julian Gannon
Institute: Cancer Research UK, London Research Institute: Clare Hall Laboratories
Tool Details
*FOR RESEARCH USE ONLY
- Name: Anti-Plx [AZ44]
- Alternate name: Polo Like Kinase 1; Serine/Threonine-Protein Kinase 13; EC 2.7.11.21; STPK13; PLK-1; Cell Cycle Regulated Protein Kinase; Polo Like Kinase; EC 2.7.11
- Clone: AZ44
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Strain: Balb/c
- Reactivity: Xenopus laevis
- Host: Mouse
- Application: WB ; ELISA ; WB
- Description: Polo-like kinase (Plx) is a mitotic regulator conserved from yeasts to humans. Many key cell cycle regulators such as p53, cdc25, cyclin B and the Anaphase Promoting Complex are directly targeted by Plx.The Anaphase promoting complex is responsible for the destruction of cyclins and other proteins involved with mitosis.
- Immunogen: Baculo expressed Polo-like-kinase from Xenopus laevis
- Isotype: IgG1 kappa
- Myeloma used: Sp2/0-Ag14
- Recommended controls: Xenopus egg extract
Target Details
- Target: Polo-like-kinase protein (Plk)
- Tissue cell line specificity: Xenopus egg extract
- Target background: Polo-like kinase (Plx) is a mitotic regulator conserved from yeasts to humans. Many key cell cycle regulators such as p53, cdc25, cyclin B and the Anaphase Promoting Complex are directly targeted by Plx.The Anaphase promoting complex is responsible for the destruction of cyclins and other proteins involved with mitosis.
Applications
- Application: WB ; ELISA ; WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- Esmaili et al. 2010. Cell Cycle. 9(19):3913-20. PMID: 20935510.
- Wu et al. 2009. Nat Cell Biol. 11(5):644-51. PMID: 19396163.
