Cat. #151291
Anti-MUS81 [MTA30 2G10/3]
Cat. #: 151291
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 3-5 days
Target: MUS81
Class: Monoclonal
Application: IF ; ICC ; FACS ; IHC ; IF ; IP ; WB
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Stephen West
Institute: Cancer Research UK, London Research Institute: Clare Hall Laboratories
Tool Details
*FOR RESEARCH USE ONLY
- Name: Anti-MUS81 [MTA30 2G10/3]
- Clone: MTA30 2G10/3
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: 60-65 kDa
- Strain: Balb/c
- Reactivity: Human
- Host: Mouse
- Application: IF ; ICC ; FACS ; IHC ; IF ; IP ; WB
- Description: MUS81 and EME1 constitute a heterodimeric endonuclease that has been implicated in mitotic and meiotic recombination in eukaryotes.
- Immunogen: Human MUS81
- Isotype: IgG2a
- Myeloma used: Sp2/0-Ag14
Target Details
- Target: MUS81
- Molecular weight: 60-65 kDa
- Target background: MUS81 and EME1 constitute a heterodimeric endonuclease that has been implicated in mitotic and meiotic recombination in eukaryotes.
Applications
- Application: IF ; ICC ; FACS ; IHC ; IF ; IP ; WB
Handling
- Format: Liquid
- Concentration: 1 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- Xu et al. 2019. Sci Adv. 5(10):eaax6366. PMID: 31633027.
- Panier et al. 2019. Mol Cell. 76(1):27-43.e11. PMID: 31447390.
- Mason et al. 2019. Nat Commun. 10(1):4410. PMID: 31562309.
- Xu et al. 2017. Elife. 6:. PMID: 29106372.
- Moder et al. 2017. Nat Commun. 8(1):1238. PMID: 29089570.
- Lema
on et al. 2017. Nat Commun. 8(1):860. PMID: 29038425. - Li et al. 2017. Mol Med Rep. 16(4):5321-5325. PMID: 28849153.
- Dungrawala et al. 2017. Mol Cell. 67(3):374-386.e5. PMID: 28735897.
- Di Marco et al. 2017. Mol Cell. 66(5):658-671.e8. PMID: 28575661.
- Lv et al. 2017. Tumour Biol. 39(3):1010428317694307. PMID: 28347251.
- Wyatt et al. 2017. Mol Cell. 65(5):848-860.e11. PMID: 28257701.
- Meisenberg et al. 2017. Nucleic Acids Res. 45(3):1159-1176. PMID: 28180300.
- Meisenberg et al. 2017. Nucleic Acids Res. 45(3):1159-1176. PMID: 28180300.
- Jo et al. 2016. PLoS Genet. 12(12):e1006465. PMID: 27906959.
- Pepe et al. 2014. Nucleic Acids Res. 42(6):3833-45. PMID: 24371268.
- CtIP is required to initiate replication-dependent interstrand crosslink repair.
- Duquette et al. 2012. PLoS Genet. 8(11):e1003050. PMID: 23144634.
- Svendsen et al. 2009. Cell. 138(1):63-77. PMID: 19596235.
- Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair.
- Franchitto et al. 2008. J Cell Biol. 183(2):241-52. PMID: 18852298.
- Replication fork stalling in WRN-deficient cells is overcome by prompt activation of a MUS81-dependent pathway.
