Cat. #151270
Anti-SCP3 [Cor 10G11/7]
Cat. #: 151270
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 1-2 weeks
Target: Synaptonemal Complex Protein 3 (SCP3; COR1)
Class: Monoclonal
Application: IF ; ELISA ; IHC ; IF ; WB
Reactivity: Hamster ; Mouse ; Zebrafish
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Madalena Tarsounas
Institute: Cancer Research UK, London Research Institute: Clare Hall Laboratories
Tool Details
*FOR RESEARCH USE ONLY
- Name: Anti-SCP3 [Cor 10G11/7]
- Clone: Cor 10G11/7
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Strain: Balb/c
- Reactivity: Hamster ; Mouse ; Zebrafish
- Host: Mouse
- Application: IF ; ELISA ; IHC ; IF ; WB
- Description: Cor 10G11/7 is an excellent tool for the visualisation of chromosomes in meiotic spreads.
- Immunogen: Hamster COR1/SCP3 protein (expressed as 6x His fusion in bacteria and purified on a Talon under denaturing conditions).
- Isotype: IgG1 kappa
- Myeloma used: Sp2/0-Ag14
Target Details
- Target: Synaptonemal Complex Protein 3 (SCP3; COR1)
- Target background: SCP3 (murine and human) / COR1 (hamster) is a component of the meiotic chromosome cores.
Applications
- Application: IF ; ELISA ; IHC ; IF ; WB
Handling
- Format: Liquid
- Concentration: 0.9-1.1 mg/ml
- Unit size: 100 ug
- Storage buffer: DMEM + 5% FCS
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- Verver et al. 2013. Cell Death Dis. 4:e749. PMID: 23907463.
- Role for rodent Smc6 in pericentromeric heterochromatin domains during spermatogonial differentiation and meiosis.
- Yamaguchi et al. 2013. Cell Res. 23(3):329-39. PMID: 23399596.
- Dynamics of 5-methylcytosine and 5-hydroxymethylcytosine during germ cell reprogramming.
- Heaney et al. 2012. Development. 139(9):1577-86. PMID: 22438569.
- Germ cell pluripotency, premature differentiation and susceptibility to testicular teratomas in mice.
- Tarsounas et al. 2004. Cell. 117(3):337-47. PMID: 15109494.
- Telomere maintenance requires the RAD51D recombination/repair protein.
