#151222

Anti-Integrin b1 [4B7]

Cat. #151222

Anti-Integrin b1 [4B7]

Cat. #: 151222

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 3-4 weeks

Target: Integrin ?1 (CD29)

Class: Monoclonal

Application: FACS ; IHC ; IF ; IP ; Fn

Reactivity: Human

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Institute: Queen Mary University of London

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Anti-Integrin b1 [4B7]
  • Clone: 4B7
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Strain: Balb/c
  • Reactivity: Human
  • Host: Mouse
  • Application: FACS ; IHC ; IF ; IP ; Fn
  • Description: Integrins are heterodimeric cell surface receptors composed of alpha and beta subunits, which mediate cell-cell and cell-extracellular matrix attachments. Aberrant integrin expression has been found in many epithelial tumours. Changes in integrin expression have been shown to be important for the growth and early metastatic capacity of melanoma cells. Loss of integrin beta 1 is associated with the development of some epithelial tumours.
  • Immunogen: Ocular melanoma cell line V+B2
  • Isotype: IgG1

Target Details

  • Target: Integrin ?1 (CD29)
  • Target background: Integrins are heterodimeric cell surface receptors composed of alpha and beta subunits, which mediate cell-cell and cell-extracellular matrix attachments. Aberrant integrin expression has been found in many epithelial tumours. Changes in integrin expression have been shown to be important for the growth and early metastatic capacity of melanoma cells. Loss of integrin beta 1 is associated with the development of some epithelial tumours.

Applications

  • Application: FACS ; IHC ; IF ; IP ; Fn

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C

References

  • Marshall et al. 1998. Br J Cancer. 77(4):522-9. PMID: 9484806.
  • Comparative analysis of integrins in vitro and in vivo in uveal and cutaneous melanomas.