Cat. #151177
Anti-Leu2 [UCH-T4]
Cat. #: 151177
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 1-2 weeks
Target: Leu2 (CD8)
Class: Monoclonal
Application: FACS ; IHC ; IF
Reactivity: Human
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Peter Beverley
Institute: Cancer Research UK, London Research Institute: Lincoln's Inn Fields
Tool Details
*FOR RESEARCH USE ONLY
- Name: Anti-Leu2 [UCH-T4]
- Clone: UCH-T4
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: 32 kDa
- Strain: Balb/c
- Reactivity: Human
- Host: Mouse
- Application: FACS ; IHC ; IF
- Description: UCH-T4 is recommended for: the detection of immunoregulatory T cell subset imbalances in autoimmune disorders and immunodeficiency states, categorisation of T cell acute lymphoblastic leukaemia and lymphoblastic lymphoma in conjunction with other antigens and determination of T4/T8 ratios in immune deficiencies, rheumatoid arthritis, multiple sclerosis, etc.
- Immunogen: Thymocytes followed by Sezary T cells.
- Isotype: IgG2a
Target Details
- Target: Leu2 (CD8)
- Molecular weight: 32 kDa
- Target background: Leu-2 is a T cell co-receptor that recognises, together with the T cell receptor, MHC class I molecules. Leu-2 is present on human suppressor / cytotoxic T cells, 30% of circulating T cells.
Applications
- Application: FACS ; IHC ; IF
Handling
- Format: Liquid
- Concentration: 0.9 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -15° C to -25° C
- Shipping conditions: Shipping at 4° C
References
- Beverley P. 1982. Proc. Royal Soc. Edin. 81B:221-232
- Waleh et al. 2011. Pediatr Res. 70(4):332-8. PMID: 21691249.
- Anatomic closure of the premature patent ductus arteriosus: The role of CD14+/CD163+ mononuclear cells and VEGF in neointimal mound formation.
- Mart
n et al. 2002. J Cutan Pathol. 29(6):347-53. PMID: 12135465. - Vascular endothelium express CS-1 fibronectin in allergic contact dermatitis.
- Kee et al. 2000. J Cell Biochem. 78(1):97-111. PMID: 10797569.
- beta1B integrin subunit contains a double lysine motif that can cause accumulation within the endoplasmic reticulum.
