#151153

Anti-Epithelia [PR 4D1]

Cat. #151153

Anti-Epithelia [PR 4D1]

Cat. #: 151153

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 10-12 weeks

Target: Epithelia (colonic)

Class: Monoclonal

Application: IHC

Reactivity: Human

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Walter Bodmer

Institute: Cancer Research UK, London Research Institute: Lincoln's Inn Fields

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Anti-Epithelia [PR 4D1]
  • Clone: PR 4D1
  • Tool type ecom: Antibodies
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Molecular weight: 140 kDa
  • Strain: Balb/c
  • Reactivity: Human
  • Host: Mouse
  • Application: IHC
  • Description: PR 4D1 may be useful for histological diagnosis of colon disorders. Wide reactivity with GI tract. Reacts with a high MW glycoprotein in human colonic mucus, epithelial cells and cell membranes.
  • Immunogen: Mucosal scrapings and membrane preparations from normal colorectal epithelium and possibly booster inoculations with the colon carcinoma cell line HT29.
  • Isotype: IgG1
  • Myeloma used: P3/NS1/1-Ag4.1

Target Details

  • Target: Epithelia (colonic)
  • Molecular weight: 140 kDa
  • Target background: PR 2D3 reacts with a cell membrane component of cells in the pericrypt sheath; with smooth muscle cells and myofibroblasts. This antibody is considered to be the gold standard for the identification of myofibroblasts.

Applications

  • Application: IHC

Handling

  • Format: Liquid
  • Concentration: 0.9-1.1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C

References

  • Richman et al. 1987. Int J Cancer. 39(3):317-28. PMID: 2434440.
  • Monoclonal antibodies to human colorectal epithelium: markers for differentiation and tumour characterization.