#151109

Anti-Integrin a3 [IA3]

Cat. #151109

Anti-Integrin a3 [IA3]

Cat. #: 151109

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 1-2 weeks

Target: Integrin a3 (CD49c)

Class: Monoclonal

Application: FACS ; IHC ; IF ; Fn

Reactivity: Human

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Joyce Taylor-Papadimitriou

Institute: Cancer Research UK, London Research Institute: Lincoln's Inn Fields

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Anti-Integrin a3 [IA3]
  • Clone: IA3
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Molecular weight: 180-220 kDa
  • Strain: Balb/c
  • Reactivity: Human
  • Host: Mouse
  • Application: FACS ; IHC ; IF ; Fn
  • Description: Monoclonal antibody with use studying inhibition of cellular adhesion.
  • Immunogen: Transfected human breast epithelial cell line MTSV1-7, hygromycin resistant.
  • Immunogen uniprot id: P26006
  • Isotype: IgG1
  • Myeloma used: P3X63Ag8.653

Target Details

  • Target: Integrin a3 (CD49c)
  • Molecular weight: 180-220 kDa
  • Target background: Monoclonal antibody with use studying inhibition of cellular adhesion.

Applications

  • Application: FACS ; IHC ; IF ; Fn

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: Store at -20° C frozen. Avoid repeated freeze / thaw cycles
  • Shipping conditions: Shipping at 4° C

References

  • Tremblay et al. 2017. Sci Rep. 7:46574. PMID: 28422167.
  • Tremblay et al. 2017. Sci Rep. 7:46574. PMID: 28422167.
  • Seltmann et al. 2015. J Invest Dermatol. 135(6):1609-1620. PMID: 25668239.
  • Seltmann et al. 2015. J Invest Dermatol. 135(6):1609-20. PMID: 25668239.
  • Keratins Stabilize Hemidesmosomes through Regulation of ?4-Integrin Turnover.
  • Stawikowski et al. 2014. J Biol Chem. 289(31):21591-604. PMID: 24958723.
  • Glycosylation modulates melanoma cell a2?1 and a3?1 integrin interactions with type IV collagen.
  • Pytlk et al. 2009. Biomaterials. 30(20):3415-27. PMID: 19362364.
  • The cultivation of human multipotent mesenchymal stromal cells in clinical grade medium for bone tissue engineering.
  • Turner et al. 2006. Circulation. 114(8):820-9. PMID: 16908762.
  • Alpha2(VIII) collagen substrata enhance endothelial cell retention under acute shear stress flow via an alpha2beta1 integrin-dependent mechanism: an in vitro and in vivo study.
  • Berdichevsky et al. 1994. J Cell Sci. 107 ( Pt 12):3557-68. PMID: 7535787.
  • Branching morphogenesis of human mammary epithelial cells in collagen gels.