#151091

Anti-HPV16E2 [EL58]

Cat. #151091

Anti-HPV16E2 [EL58]

Cat. #: 151091

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 1-2 weeks

Target: Human Papilloma virus-16 early protein 2 (HPV16 E2)

Class: Monoclonal

Application: WB

Reactivity: Human papilloma virus

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Emma Lees

Institute: University of Oxford

Tool Details
Target Details
Applications
Handling
Related Tools
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Anti-HPV16E2 [EL58]
  • Clone: EL58
  • Tool type ecom: Antibodies
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Molecular weight: 175 kDa
  • Strain: Balb/c
  • Reactivity: Human papilloma virus
  • Host: Mouse
  • Application: WB
  • Description: The human papilloma virus (HPV) family of DNA tumor viruses includes HPV-16 and HPV-18, which are associated with a large proportion of cervical cancer cases. E1 and E2 are proteins involved in the regulation of viral DNA replication.
  • Immunogen: Bacterial recombinant protein
  • Immunogen uniprot id: P00533
  • Isotype: IgG1
  • Myeloma used: NS0

Target Details

  • Target: Human Papilloma virus-16 early protein 2 (HPV16 E2)
  • Molecular weight: 175 kDa
  • Target background: The human papilloma virus (HPV) family of DNA tumor viruses includes HPV-16 and HPV-18, which are associated with a large proportion of cervical cancer cases. E1 and E2 are proteins involved in the regulation of viral DNA replication.

Applications

  • Application: WB

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C

Related Tools

  • Related tools: Anti-EGFR, Recombinant [EGFR1]

References

  • Finetti et al. 2015. Endocr Relat Cancer. 22(4):665-78. PMID: 26113609.
  • Perillo et al. 2015. Nat Commun. 6:7874. PMID: 26219252.
  • Tang et al. 2015. Oncol Rep. 34(1):350-8. PMID: 25955689.
  • mPGES-1 in prostate cancer controls stemness and amplifies epidermal growth factor receptor-driven oncogenicity.
  • Downregulation of CD9 promotes pancreatic cancer growth and metastasis through upregulation of epidermal growth factor on the cell surface.
  • Boersma et al. 2011. J Biol Chem. 286(48):41273-85. PMID: 21979953.
  • Bispecific designed ankyrin repeat proteins (DARPins) targeting epidermal growth factor receptor inhibit A431 cell proliferation and receptor recycling.
  • Jensen et al. 2006. Proc Natl Acad Sci U S A. 103(32):11958-63. PMID: 16877544.
  • Single-cell expression profiling of human epidermal stem and transit-amplifying cells: Lrig1 is a regulator of stem cell quiescence.
  • Gullick et al. 1986. Cancer Res. 46(1):285-92. PMID: 2998607.
  • Expression of epidermal growth factor receptors on human cervical, ovarian, and vulval carcinomas.
  • Waterfield et al. 1982. J Cell Biochem. 20(2):149-61. PMID: 6188757.
  • A monoclonal antibody to the human epidermal growth factor receptor.