#151078

Anti-HLA-B7 [BB7.1]

Cat. #151078

Anti-HLA-B7 [BB7.1]

Cat. #: 151078

Sub-type: Primary antibody

Unit size: 100 ug

Availability: 1-2 weeks

Target: HLA-B7

Class: Monoclonal

Application: FACS ; FACS

Reactivity: Human

Host: Mouse

£300.00

This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.

Contributor

Inventor: Walter Bodmer

Institute: Cancer Research UK, London Research Institute: Lincoln's Inn Fields

Tool Details
Target Details
Applications
Handling
References

Tool Details

*FOR RESEARCH USE ONLY

  • Name: Anti-HLA-B7 [BB7.1]
  • Clone: BB7.1
  • Tool type ecom: Antibodies
  • Tool sub type: Primary antibody
  • Class: Monoclonal
  • Conjugation: Unconjugated
  • Strain: Balb/c
  • Reactivity: Human
  • Host: Mouse
  • Application: FACS ; FACS
  • Description: This antibody can be used for HLA typing.
  • Immunogen: Papain solubilised HLA-A2, B7
  • Isotype: IgG1
  • Myeloma used: P3/NS1/1-Ag4.1

Target Details

  • Target: HLA-B7
  • Target background: Human Leukocyte Antigens are highly polymorphic proteins that are involved in the presentation of antigens to the T-cell receptor. There are two classes of HLA antigens, class I (HLA-A, HLA-B and HLA-C) and class II (HLA-D).

Applications

  • Application: FACS ; FACS

Handling

  • Format: Liquid
  • Concentration: 1 mg/ml
  • Unit size: 100 ug
  • Storage buffer: PBS with 0.02% azide
  • Storage conditions: -15° C to -25° C
  • Shipping conditions: Shipping at 4° C

References

  • Reches et al. 2016. J Immunol. :. PMID: 27194785.
  • HNRNPR Regulates the Expression of Classical and Nonclassical MHC Class I Proteins.
  • Dellgren et al. 2015. PLoS One. 10(8):e0135385. PMID: 26258424.
  • Cell surface expression level variation between two common Human Leukocyte Antigen alleles, HLA-A2 and HLA-B8, is dependent on the structure of the C terminal part of the alpha 2 and the alpha 3 domains.
  • Rancan et al. 2015. PLoS Pathog. 11(6):e1004906. PMID: 26067064.
  • Latent Membrane Protein LMP2A Impairs Recognition of EBV-Infected Cells by CD8+ T Cells.
  • Levering et al. 2000. Cytometry. 42(2):95-105. PMID: 10797446.
  • External quality assessment of flow cytometric HLA-B27 typing.
  • Parham et al. 1981. Hum Immunol. 3(4):277-99. PMID: 7035415.
  • Partial purification and some properties of BB7.2. A cytotoxic monoclonal antibody with specificity for HLA-A2 and a variant of HLA-A28.
  • Brodsky et al. 1979. Immunol Rev. 47:3-61. PMID: 95015.
  • Monoclonal antibodies for analysis of the HLA system.