Cat. #151064
Anti-Cytochrome P450 2B1, 2B2 [b/e3]
Cat. #: 151064
Sub-type: Primary antibody
Unit size: 100 ug
Availability: 1-2 weeks
Target: Cytochromes P450 2B1, 2B2, CYP2B1, CYP2B2
Class: Monoclonal
Application: ELISA ; IP ; WB
Reactivity: Mouse ; Rat
Host: Mouse
£300.00
This fee is applicable only for non-profit organisations. If you are a for-profit organisation or a researcher working on commercially-sponsored academic research, you will need to contact our licensing team for a commercial use license.
Contributor
Inventor: Roland Wolf
Institute: University of Dundee
Tool Details
*FOR RESEARCH USE ONLY
- Name: Anti-Cytochrome P450 2B1, 2B2 [b/e3]
- Clone: b/e3
- Tool type ecom: Antibodies
- Tool sub type: Primary antibody
- Class: Monoclonal
- Conjugation: Unconjugated
- Molecular weight: 52 kDa
- Strain: Balb/c
- Reactivity: Mouse ; Rat
- Host: Mouse
- Application: ELISA ; IP ; WB
- Description: The CYP2 family are part of the microsomal drug metabolising system that is responsible for oxidation of many therapeutic agents as well as steroids, fatty acids and many other endogenous substances. CYP2B1 and CYP2B2 are the major phenobarbital-inducible rat hepatic cytochromes P450s. This reagent was created through a research collaboration between Cancer Research UK and Syngenta Crop Protection AG.
- Immunogen: Rat liver cytochromes p450 2B1 and 2B2
- Isotype: IgG1
- Myeloma used: Sp2/0-Ag14
- Recommended controls: LnCap cells
Target Details
- Target: Cytochromes P450 2B1, 2B2, CYP2B1, CYP2B2
- Molecular weight: 52 kDa
- Tissue cell line specificity: LnCap cells
- Target background: The CYP2 family are part of the microsomal drug metabolising system that is responsible for oxidation of many therapeutic agents as well as steroids, fatty acids and many other endogenous substances. CYP2B1 and CYP2B2 are the major phenobarbital-inducible rat hepatic cytochromes P450s. This reagent was created through a research collaboration between Cancer Research UK and Syngenta Crop Protection AG.
Applications
- Application: ELISA ; IP ; WB
Handling
- Format: Liquid
- Concentration: 0.84 mg/ml
- Unit size: 100 ug
- Storage buffer: PBS with 0.02% azide
- Storage conditions: -20° C
- Shipping conditions: Shipping at 4° C
References
- Chanyshev et al. 2020. Toxicol Mech Methods. 30(8):562-569. PMID: 32508177.
- Rencurel et al. 2005. J Biol Chem. 280(6):4367-73. PMID: 15572372.
- AMP-activated protein kinase mediates phenobarbital induction of CYP2B gene expression in hepatocytes and a newly derived human hepatoma cell line.
- Forrester et al. 1992. Biochem J. 281 ( Pt 2):359-68. PMID: 1736885.
- Relative expression of cytochrome P450 isoenzymes in human liver and association with the metabolism of drugs and xenobiotics.
