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p53 Pathway Antibodies

Mouse anti-p53 Monoclonal Antibody, Purified [DO-1]

Name: Mouse anti-p53 Monoclonal Antibody, Purified [DO-1]
Brand: Bethyl Laboratories®
SKU: A500-015A
Price: 127 USD

Bethyl Laboratories®

Catalog #

Citations (6)

Target:

p53

Reactivity:

Human

Applications:

, , ,

Platforms:

COMET™

Host:

Mouse

Clonality:

Monoclonal

Clone:

DO-1

Format:

Whole IgG

Immunogen:

Recombinant full length protein corresponding to Human p53 (N terminal). epitope is within aa 20-25

Isotype:

IgG2a

Conjugate:

Unconjugated

Purity:

Purified

100 µl (10 blots)

20 µl (2 blots)

100 µg (BSA-Free)

Product Details

Specifications

Verified Reactivity

Human

Antigen Species

Human

Concentration

100 µg/ml 1000 µg/ml

Storage

2 - 8 °C

Shelf Life

1 year from date of receipt

Physical State

Liquid

Buffer

Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide

Request Formulation Change

Tris-buffered Saline containing 0.09% Sodium Azide, BSA-Free

Request Formulation Change

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Additional Product Information

p53 is a tumor suppressor protein that is mutated or inactivated in over 50% of human cancers. Loss of function defects in p53 are the cause of the autosomal dominant familial cancer syndrome, Li-Fraumeni syndrome (LFS) that is characterized by the development of a diverse set of malignancies at very early ages. At the cellular level p53 is involved in the negative regulation of cell the cycle via its transactivational control of genes required for cell cycle progression. Depending on the physiological circumstance, p53 can promote growth arrest or apoptosis.

Gene ID:

7157

Gene Symbol:

TP53

Gene Name:

tumor protein p53

Uniprot ID:

P04637

Protein Name:

Cellular tumor antigen p53

Alternate Names

antigen NY-CO-13; BCC7; cellular tumor antigen p53; LFS1; mutant tumor protein 53; P53; p53 tumor suppressor; phosphoprotein p53; transformation-related protein 53; TRP53; tumor protein 53; Tumor suppressor p53; tumor supressor p53

Applications

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots are performed using Goat anti-Mouse IgG Heavy and Light Chain Antibody (Cat. No. A90-216P).

Mouse anti-p53 Monoclonal Antibody, Purified [DO-1]

Catalog #

p53

Human

Flow Cyt

IHC

IP

WB

COMET™

Mouse

Monoclonal

DO-1

Whole IgG

Recombinant full length protein corresponding to Human p53 (N terminal). epitope is within aa 20-25

IgG2a

Unconjugated

Purified

Human

Human

2 - 8 °C

1 year from date of receipt

Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide

Tris-buffered Saline containing 0.09% Sodium Azide, BSA-Free

7157

TP53

tumor protein p53

P04637

Cellular tumor antigen p53

antigen NY-CO-13; BCC7; cellular tumor antigen p53; LFS1; mutant tumor protein 53; P53; p53 tumor suppressor; phosphoprotein p53; transformation-related protein 53; TRP53; tumor protein 53; Tumor suppressor p53; tumor supressor p53

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.Western blots are performed using Goat anti-Mouse IgG Heavy and Light Chain Antibody (Cat. No. A90-216P).

All western blot analysis is performed using 5% Milk-TBST for blocking and as antibody diluent. Primary antibody is incubated overnight.

Western blots are performed using Goat anti-Mouse IgG Heavy and Light Chain Antibody (Cat. No. A90-216P).