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{{/_source.additionalInfo}}Anti-Cytochrome P450 4V2 [M29-P3B10]
(Cat#: 152159)
Description
| Cat# | 152159 |
| Applications | ELISA, IHC, WB |
| Antigen/Gene or Protein Targets | Cytochrome P450, family 4, subfamily V, polypeptide 2 (CYP4V2) |
| Synonyms | Cytochrome P450; Family 4; Subfamily V; Polypeptide 2; Docosahexaenoic Acid Omega-Hydroxylase CYP4V2; CYP4AH1; BCD |
| Reactivity | Human |
| Relevance | Cytochrome P450, family 4, subfamily V, polypeptide 2 (CYP4V2) encodes a member of the cytochrome P450 superfamily of enzymes that are a group of heme-thiolate monooxygenases. Cytochromes P450 catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. CYP4V2 catalyzes the omega-hydroxylation of medium-chain saturated fatty acids such as laurate, myristate and palmitate in an NADPH-dependent pathway. CYP4V2 may have a role in fatty acid and steroid metabolism in the eye and its mutations are associated with Bietti's crystalline dystrophy (BCD) and retinitis pigmentosas. |
| Host | Mouse |
| Immunogen | Peptide sequence – KREELGLEGQ (amino acids 495 – 504) |
| Positive Control |
ELISA- Peptide immunogen Western Blot- Human liver microsomes IHC- Human liver |
| Subclass | IgG1 kappa |
| Myeloma Used | P3X63Ag8.653 |
| Recommended Growing Conditions | Dulbecco’s media containing 20% Fetal Bovine serum (DH20) prepared as follows (for final volume of 300ml: 237ml DMEM + 60 ml Fetal Bovine Serum + 3ml L-Glutamine + 3ml of Penicillin -Streptomycin. |
| Strain | Balb/c |
| Research Area | Cancer, Cardiovascular, Cell Signaling & Signal Transduction, Metabolism |
| References | The differential expression of omega-3 and omega-6 fatty acid metabolising enzymes in colorectal cancer and its prognostic significance. Europe PMC ID: 28557975 |
For Research Use Only.
