Cancer Research Technology
Log in Register
Menu

Transient receptor potential ankyrin 1 (TRPA1)-GFP HeLa cell line

Invented by Peter Bradding , Harvinder Virk
Invented at University Of Leicester

Info

Catalogue Number 158381
Antigen/Gene or Protein Targets human Transient receptor potential cation channel family member ankyrin 1 (hTRPA1)
Parental Line HeLa
Relevance The transient receptor potential cation channel family member ankyrin 1 (TRPA1) is an ion channel with high Ca2+ permeability that is activated by numerous noxious stimuli and by multiple products of oxidative stress. TRPA1 is a drug target with antagonists in phase I and II clinical trials. It is considered a potential target in multiple pain conditions including neuropathic, inflammatory and migraine pain, in addition to cough sensitivity, airway inflammation and fibrosis

This HeLa cell line is stably transfected with a dual-gene promotor (pCDH-CMV-MCS-EF1-copGFP) to express both GFP and hTRPA1.
Conditional No
Research Area Neurobiology
Notes Forward TRPA1 Xba1 gggtctagaATGAAGCGCAGCCTGAGGAAG

Reverse TRPA1 NotI ggggcggccgcttaAGGCTCAAGATGGTGTGTTTTTGCC

References

There are 1 reference entries for this reagent.

View All References

References: 1 entry

Virk et al. 2019. Sci Rep. 9(1):18500. PMID: 31811235.


Add a reference

References: 1 entry

Virk et al. 2019. Sci Rep. 9(1):18500. PMID: 31811235.


Add a reference

Inventor Information

Inventors

Peter Bradding

Peter Bradding

Harvinder Virk

Harvinder Virk

Add an inventor