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PlasmaxTM cell culture medium

Invented by Saverio Tardito
Invented at Cancer Research UK Glasgow: The Beatson Institute

Info

Catalogue Number 156371
Relevance Background and Research Application

PlasmaxTM is a new physiologically relevant cell culture medium which mimics the metabolic and physiological profile of human plasma. It is designed to improve the metabolic fidelity and biological relevance of in vitro cancer models by recapitulating the natural in vivo metabolic environment in an in vitro setting.

Researchers have found that conventional growth-focused media with non-physiological concentrations of nutrients and metabolites can skew the metabolic profile of cancer cells. PlasmaxTM is optimised from over 80 components, including amino acids and derivatives, inorganic salts, trace elements, and vitamins, of which over 50 are at levels found in human plasma. PlasmaxTM is also the only ready-to-use cell culture media containing growth-enhancing trace elements including vanadium, zinc, manganese, copper and selenium.

PlasmaxTM formulation compared to conventional media.

PlasmaxTM can be used by cancer researchers interested in cancer cell biology. It has been validated for growth performance and metabolic fidelity in several widely-used triple-negative breast cancer cell lines.

Read the PlasmaxTM application note.

Learn more about PlasmaxTM here.
Volume (mL) 500
Notes PlasmaxTM is a complete and ready-to-use cell culture medium.

PlasmaxTM is stable for twelve months at 4°C.

Have a question about PlasmaxTM? See some frequently asked questions here.

Please see the PlasmaxTM Material Safety Data Sheet (MSDS) here.

References

There are 24 reference entries for this reagent.

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References: 24 entries

Bagshaw et al. 2021. Biomaterials and Biosystems.4 (100027): 2666-5344

Gassl et al. Cancers (Basel) 2022 Nov 16,14(22):5617. PMID: 36428711

Golikov et al. 2022. Antioxidants 2022, 11, 97.

Bagshawet al. Mitochondrial Intoxication. 2023, 723-744

Wang et al. Biomolecules 2022 Oct 27,12(11):1575. PMID: 36358924

Villar et al. 2022. Nat Chem Biol. PMID: 36280791

Gassl et al. Cancers (Basel) 2022 Nov 16,14(22):5617. PMID: 36428711

Golikov et al. 2022. Mol Biol (Mosk) 56(5):687-696. PMID: 36165010

Gardner et al. 2022. Am J Physiol Cell Physiol 323(3):C823-C834. PMID: 35876286

Golikov et al. Antioxidants 2022, 11(1), 97

Kalimuthu et al. 2021. J Cell Biochem. :. PMID: 34935169.

Hennequart et al. 2021. Nature Communications. 12: 6176.

Chiu et al. 2021. American Society of Hematology. Blood Advances.

Cox et al. 2020. Journal of Data and Information Science. 5(3): 161-177

Moradi et al. 2021. Biomolecules. 11(8): 1177

Plasmax Application Note

Barekatain et al. 2021. Nature. 12: 4228.

Moradi et al. 2021. American Journal of Physiology. Cell Physiology. 321 (1): C72-C81.

Khadka et al. 2021. Cancer & Metabolism. 9:27

Abbas et al. 2021. Comp Biochem Physiol B Biochem Mol Biol. 254:110570. PMID: 33516822.

PlasmaxTM: Product Brochure

Ackermann et al. 2019. Trends Cancer. 5(6):329-332. PMID: 31208694.

Cell culture shock – a scientist’s hunt for the perfect cocktail

Vande Voorde et al. 2019. Sci Adv. 5(1):eaau7314. PMID: 30613774.


Add a reference

References: 24 entries

Bagshaw et al. 2021. Biomaterials and Biosystems.4 (100027): 2666-5344

Gassl et al. Cancers (Basel) 2022 Nov 16,14(22):5617. PMID: 36428711

Golikov et al. 2022. Antioxidants 2022, 11, 97.

Bagshawet al. Mitochondrial Intoxication. 2023, 723-744

Wang et al. Biomolecules 2022 Oct 27,12(11):1575. PMID: 36358924

Villar et al. 2022. Nat Chem Biol. PMID: 36280791

Gassl et al. Cancers (Basel) 2022 Nov 16,14(22):5617. PMID: 36428711

Golikov et al. 2022. Mol Biol (Mosk) 56(5):687-696. PMID: 36165010

Gardner et al. 2022. Am J Physiol Cell Physiol 323(3):C823-C834. PMID: 35876286

Golikov et al. Antioxidants 2022, 11(1), 97

Kalimuthu et al. 2021. J Cell Biochem. :. PMID: 34935169.

Hennequart et al. 2021. Nature Communications. 12: 6176.

Chiu et al. 2021. American Society of Hematology. Blood Advances.

Cox et al. 2020. Journal of Data and Information Science. 5(3): 161-177

Moradi et al. 2021. Biomolecules. 11(8): 1177

Plasmax Application Note

Barekatain et al. 2021. Nature. 12: 4228.

Moradi et al. 2021. American Journal of Physiology. Cell Physiology. 321 (1): C72-C81.

Khadka et al. 2021. Cancer & Metabolism. 9:27

Abbas et al. 2021. Comp Biochem Physiol B Biochem Mol Biol. 254:110570. PMID: 33516822.

PlasmaxTM: Product Brochure

Ackermann et al. 2019. Trends Cancer. 5(6):329-332. PMID: 31208694.

Cell culture shock – a scientist’s hunt for the perfect cocktail

Vande Voorde et al. 2019. Sci Adv. 5(1):eaau7314. PMID: 30613774.


Add a reference