Anti-XRCC3 [XRCC3 10F1/6] recombinant antibody
Invented at Cancer Research UK London Research Institute: Clare Hall Laboratories
- Datasheet
- References (6)
- Inventor Info
Info
Catalogue Number | 154844 |
Applications | N/A |
Antigen/Gene or Protein Targets | XRCC3 |
Reactivity | Human |
Relevance | X-Ray Repair Cross Complementing 3 (XRCC3) is a RAD51 paralog. RAD51 is a eukaryotic homologue of E. coli RecA, a recombinase, and a component of the homologous recombination DNA repair pathway. RAD51 forms a nucleoprotein filament (through binding RAD52 and single stranded DNA that are exposed following double strand breaks) that initiates recombination. XRCC3 is also a component of the homologous recombination pathway. |
Host | Mouse |
Immunogen | His-tagged human XRCC3 |
Subclass | IgG1 |
Positive Control | HeLa nuclear extracts. |
Molecular Weight (kDa) | 37.8 |
Research Area | Bacteriology, DNA Damage and Repair, Epigenetics & Nuclear Signalling |
References: 6 entries
Complex formation by the human RAD51C and XRCC3 recombination repair proteins.
Correction of chromosomal instability and sensitivity to diverse mutagens by a cloned cDNA of the XRCC3 DNA repair gene.
Identification and purification of two distinct complexes containing the five RAD51 paralogs.
Masson et al. 2001. Genes Dev. 15(24):3296-307. PMID: 11751635.
Masson et al. 2001. Proc Natl Acad Sci U S A. 98(15):8440-6. PMID: 11459987.
Tebbs et al. 1995. Proc Natl Acad Sci U S A. 92(14):6354-8. PMID: 7603995.
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References: 6 entries
Complex formation by the human RAD51C and XRCC3 recombination repair proteins.
Correction of chromosomal instability and sensitivity to diverse mutagens by a cloned cDNA of the XRCC3 DNA repair gene.
Identification and purification of two distinct complexes containing the five RAD51 paralogs.
Masson et al. 2001. Genes Dev. 15(24):3296-307. PMID: 11751635.
Masson et al. 2001. Proc Natl Acad Sci U S A. 98(15):8440-6. PMID: 11459987.
Tebbs et al. 1995. Proc Natl Acad Sci U S A. 92(14):6354-8. PMID: 7603995.
Add a reference