Anti-CD8 [SPVT8] monoclonal Antibody
Invented at Netherlands Cancer Institute
- Datasheet
- References (2)
- Inventor Info
Info
| Catalogue Number | 154794 |
| Applications | FACS IP |
| Antigen/Gene or Protein Targets | CD8 |
| Synonyms | Leu2 T-Lymphocyte Antigen; OKT8 T-Cell Antigen |
| Reactivity | Human |
| Relevance |
CD8 is a transmembrane glycoprotein that serves as a co-receptor for the T cell receptor (TCR). Like the TCR, CD8 binds to a major histocompatibility complex (MHC) molecule, but is specific for the class I MHC protein. The CD8 co-receptor is predominantly expressed on the surface of cytotoxic T cells, but can also be found on natural killer cells, cortical thymocytes, and dendritic cells. The CD8 molecule is a marker for cytotoxic T cell population. It is expressed in T cell lymphoblastic lymphoma and hypo-pigmented mycosis fungoides |
| Host | Mouse |
| Immunogen | Human cytotoxic T-lymphocytes |
| Subclass | IgG1 |
| Molecular Weight (kDa) | 32 |
| Myeloma Used | Sp2/0-Ag14 |
| Strain | Balb/c |
| Notes | Fusion partners: SP2/0 x spleen cells origin BALB/C. |
| Research Area | Cell Type or Organelle Marker, Immunology |
References: 2 entries
de Vries et al. 1984. J Immunol. 132(1):510-9. PMID: 6197458.
Spits et al. 1983. Hybridoma. 2(4):423-37. PMID: 6332061.
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References: 2 entries
de Vries et al. 1984. J Immunol. 132(1):510-9. PMID: 6197458.
Spits et al. 1983. Hybridoma. 2(4):423-37. PMID: 6332061.
Add a reference
