Anti-CD39 (ENTPD1) [R22] monoclonal antibody
Invented at Netherlands Cancer Institute
- Datasheet
- References (2)
- Inventor Info
Info
| Catalogue Number | 154786 |
| Applications | FACS |
| Antigen/Gene or Protein Targets | CD39 |
| Synonyms | Ectonucleoside Triphosphate Diphosphohydrolase; Ecto-ATPDase |
| Reactivity | Human |
| Relevance | CD39 is a typical cell surface-located enzymes with an extracellularly facing catalytic site. It is an ectonucleotidase that catalyse the hydrolysis of γ- and β-phosphate residues of triphospho- and diphosphonucleosides to the monophosphonucleoside derivative. For example, it hydrolyses P2 receptor ligands, namely ATP, ADP, UTP and UDP with similar efficacy. It can therefore affect P2 receptor activation and functions |
| Host | Rat |
| Immunogen | JY cells |
| Subclass | IgG1 |
| Molecular Weight (kDa) | 78 |
| Myeloma Used | Sp2/0-Ag14 |
| Recommended Growing Conditions | IMDM + 10% FBS ulta low IgG, 37 ⁰C 5% CO2 |
| Strain | Balb/c |
| Notes | Fusion partners: SP2/0 x spleen cells origin Wag/Rij. |
| Research Area | Cell Signaling & Signal Transduction |
References: 2 entries
Gouttefangeas et al. 1992. Eur J Immunol. 22(10):2681-5. PMID: 1396972.
Kansas et al. 1991. J Immunol. 146(7):2235-44. PMID: 1672348.
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References: 2 entries
Gouttefangeas et al. 1992. Eur J Immunol. 22(10):2681-5. PMID: 1396972.
Kansas et al. 1991. J Immunol. 146(7):2235-44. PMID: 1672348.
Add a reference
