Anti-CD71 (Transferrin receptor ) [66IG10] monoclonal antibody
Invented at Netherlands Cancer Institute
- Datasheet
- References (2)
- Inventor Info
Info
| Catalogue Number | 154756 |
| Applications | FACS IHC IF IP |
| Antigen/Gene or Protein Targets | CD71 |
| Synonyms | TFRC; P90 |
| Reactivity | Human |
| Relevance | Transferrin is a transmembrane glycoprotein composed of two disulfide-linked monomers joined by two disulfide bonds. Transferrin is required for iron import from transferrin into cells by endocytosis. Transferrin as a potential new target in cases of human leukaemia & lymphoma |
| Host | Mouse |
| Immunogen | Human T cells |
| Subclass | IgG1 |
| Molecular Weight (kDa) | 95 |
| Myeloma Used | Sp2/0-Ag14 |
| Recommended Growing Conditions | IMDM + 1% ZAP, 37 ⁰C 5% CO2 |
| Strain | Balb/c |
| Notes |
Fusion partners: fusion of SP2/0 Mouse myeloma cells with spleen cells from a BALB/c Mouse. This antibody reacts with the transferrin receptor, a 180-190 kDa transmembrane glycoprotein which exists as a 95 kD homodimer with interchain disulfide bond. |
| Research Area | Cellular Transport |
References: 2 entries
Moolenaar et al. 1990. Cancer Res. 50(4):1102-6. PMID: 2153450.
van de Rijn et al. 1983. Cytogenet Cell Genet. 36(3):525-31. PMID: 6315310.
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References: 2 entries
Moolenaar et al. 1990. Cancer Res. 50(4):1102-6. PMID: 2153450.
van de Rijn et al. 1983. Cytogenet Cell Genet. 36(3):525-31. PMID: 6315310.
Add a reference
