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Anti-human IGF-1 receptor (IGF-1R) [24-58] monoclonal antibody

Invented at University of Cambridge

Info

Catalogue Number 154020
Applications N/A
Antigen/Gene or Protein Targets Human Insulin-like Growth Factor-1 receptor
Synonyms IGF-1 R
Reactivity Human
Relevance Human insulin-like growth factor 1 (IGF-1) receptor is transmembrane tyrosine kinase receptor for insulin-like growth factor 1 hormone. Also activated by IGF-2. IGF receptor plays a crucial role in growth and anabolic metabolism in adults.
Host Mouse
Immunogen Murine fibroblasts over-expressing cloned human IGF-1 receptor
Subclass IgG2a
Molecular Weight (kDa) 135
Myeloma Used NS1/0
Recommended Growing Conditions Dulbecco's MEM + 20% FBS
Notes Not tested for any specific application. May work in IP, ELISA, FACS, IF, RIA. Inhibits ligand binding.
Research Area Cell Signaling & Signal Transduction, Metabolism

References

There are 2 reference entries for this reagent.

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References: 2 entries

Soos et al. 1992. J Biol Chem. 267(18):12955-63. PMID: 1377676.

A panel of monoclonal antibodies for the type I insulin-like growth factor receptor. Epitope mapping, effects on ligand binding, and biological activity.

Europe PMC ID: 1377676


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References: 2 entries

Soos et al. 1992. J Biol Chem. 267(18):12955-63. PMID: 1377676.

A panel of monoclonal antibodies for the type I insulin-like growth factor receptor. Epitope mapping, effects on ligand binding, and biological activity.


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