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Anti-human insulin receptor (IR) [25-49] monoclonal antibody

Invented at University of Cambridge

Info

Catalogue Number 154010
Applications N/A
Antigen/Gene or Protein Targets Human Insulin receptor
Synonyms IR, hIR, INSR
Reactivity Human
Relevance Human Insulin Receptor (IR) is a transmembrane tyrosine kinase receptor for insulin. It plays a role in glucose homeostasis by controlling the glucose transport to cells. Malfunction of IR include clinical manifestations such as cancer and diabetes.
Host Mouse
Immunogen Affinity-purified human insulin receptor
Subclass IgG1
Molecular Weight (kDa) 135
Myeloma Used NS1/0
Recommended Growing Conditions Dulbecco's MEM + 20% FBS
Notes Not tested for any specific application. May work in IP, ELISA, FACS, IF, RIA. Inhibits ligand binding.
Research Area Cell Signaling & Signal Transduction, Metabolism

References

There are 2 reference entries for this reagent.

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References: 2 entries

Soos et al. 1986. Biochem J. 235(1):199-208. PMID: 2427071.

Monoclonal antibodies reacting with multiple epitopes on the human insulin receptor.

Europe PMC ID: 2427071


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References: 2 entries

Soos et al. 1986. Biochem J. 235(1):199-208. PMID: 2427071.

Monoclonal antibodies reacting with multiple epitopes on the human insulin receptor.


Add a reference

Inventor Information

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