Anti-CYE1 [17C8]
Invented at University of Georgia
- Datasheet
- References (2)
- Inventor Info
Info
| Catalogue Number | 153927 |
| Applications | IF WB |
| Antigen/Gene or Protein Targets | Cyclin E |
| Synonyms | CYE-1 |
| Relevance | Cyclin E is a member of the cyclin family of proteins, which regulates the cell cycle through its activation of cyclin-dependent kinases. Specifically, cyclin E binds and activates the S phase Cdk2. The cyclin E–Cdk2 complex promotes the G1 to S phase cell cycle transition. Overexpression of cyclin E has been implicated in carcinomas among the gastrointestinal tract, including colon or stomach cancer as well as a marker for breast cancers |
| Host | Mouse |
| Immunogen | Full-length recombinant CYE-1 protein |
| Notes | This mouse monoclonal antibody was generated against full-length recombinant cyclin E (CYE-1) protein and is specific for Caenorhabditis elegans CYE-1 full-length recombinant protein (prepared in bacteria) and has been validated for use in WB, IF (1:100-300). |
| Research Area | Cell Cycle |
References: 2 entries
Kim et al. 2007. Mol Cell Biol. 27(4):1394-406. PMID: 17145765.
The Caenorhabditis elegans replication licensing factor CDT-1 is targeted for degradation by the CUL-4/DDB-1 complex.
Europe PMC ID: 17145765
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References: 2 entries
Kim et al. 2007. Mol Cell Biol. 27(4):1394-406. PMID: 17145765.
The Caenorhabditis elegans replication licensing factor CDT-1 is targeted for degradation by the CUL-4/DDB-1 complex.
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