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Anti-galβ1-4glcnac epitope [6B4]

Invented by Prof Michael Apicella from The University Of Iowa
Invented at The University Of Iowa

Info

Catalogue Number 153693
Applications N/A
Antigen/Gene or Protein Targets lactosamine (galβ1-4glcnac) epitope found in lipooligosaccharide (LOS) of pathogenic Neisseria species
Reactivity Neisseria sp., Neisseria gonorrhoeae and Neisseria meningitidis
Relevance N. gonorrhoeae is a human adapted pathogen that infects the reproductive tracts of both male and females causing pelvic inflammatory disease (PID). In females, infection often goes undetected subsequently leading to issues with infertility
Host Mouse
Subclass IgM kappa
Notes Shown to bind terminal lactosamine (galβ1-4glcnac epitope) sugar in N. gonorrhoeae biofilm. Recognizes conserved LOS epiptope on over 200 gonococcal strains. Useful for researchers studying the biology and pathology of gonococcal infections.
Research Area Bacteriology, Immunology, Microbiology

References

There are 2 reference entries for this reagent.

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References: 2 entries

Greiner et al. 2005. Infect Immun. 73(4):1964-70. PMID: 15784536.

Biofilm Formation by Neisseria gonorrhoeae.

Europe PMC ID: 15784536


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References: 2 entries

Greiner et al. 2005. Infect Immun. 73(4):1964-70. PMID: 15784536.

Biofilm Formation by Neisseria gonorrhoeae.


Add a reference