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Catalogue Number 153691
Parental Line Msh3-/- SVG-A Cell Line
Host Human
Tissue Brain
Relevance This cell line was derived from the SVG-A Msh3-/- (knock-out generated by CRISPR)) cell line whereby the DNA mismatch repair protein Msh3 expression has been reinstated.
Research Area DNA Damage and Repair, Neurobiology, Virology
Recommended Growing Conditions DMEM supplemented with 10% FBS
Notes CRISPR edited cells.

Cancer Research Technology Limited (trading research tools as Ximbio) has been granted a non-exclusive license to the CRISPR-Cas9 technology by ERS Genomics Ltd under the patent rights listed here.

This license from ERS Genomics Ltd allows Ximbio to develop and commercialise CRISPR-Cas9 modified cell lines for research use only. Ximbio can provide these modified CRISPR-Cas9 cell lines to companies under a label-use only license.

References

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References: 1 entry

Keogh et al. 2017. MutSβ abundance and Msh3 ATP hydrolysis activity are important drivers of CTG•CAG repeat expansions. Nucleic Acids Res. 2017 Sep 29;45(17):10068-10078.


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References: 1 entry

Keogh et al. 2017. MutSβ abundance and Msh3 ATP hydrolysis activity are important drivers of CTG•CAG repeat expansions. Nucleic Acids Res. 2017 Sep 29;45(17):10068-10078.


Add a reference