Anti-Myelin Basic Protein (region 129-138) [MBP1]
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- References (12)
- Inventor Info
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| Catalogue Number | 153640 |
| Applications | ELISA IHC WB |
| Antigen/Gene or Protein Targets | Myelin Basic Protein (region 129-138) |
| Synonyms |
Myelin basic protein, MBP, 20 kDa microtubule-stabilizing protein, Myelin A1 protein |
| Reactivity | Human and Rat |
| Relevance | Myelin Basic Protein (MBP) is involved in the process of myelination of nerves. MBP Clone 1 recognizes an epitope in the 129-138 region of MBP, useful in clinical diagnosis to detect MBP levels. |
| Host | Mouse |
| Immunogen | Reacts with MBP from human, bovine and rat, recognizing epitope 129-138 |
| Positive Control | Brain tissue |
| Subclass | IgG2a |
| Molecular Weight (kDa) | 13-21 |
| Myeloma Used | NS0 |
| Notes |
Suggested dilutions for use Western Blot 1:10 – 1:200 Immunohistochemistry 1:10 ELISA 1:200 – 1:1000 Immunocytochemistry 1:3000 Research Areas: Neurobiology; Cell Type or Organelle Marker;Immunology ;Genetics;Infectious diseases |
| Research Area | Cell Type or Organelle Marker, Immunology, Neurobiology |
References: 12 entries
Marignier et al. 2010. Brain. 133(9):2578-91. PMID: 20688809.
Oligodendrocytes are damaged by neuromyelitis optica immunoglobulin G via astrocyte injury.
Europe PMC ID: 20688809
Jatana et al. 2006. Pediatr Res. 59(5):684-9. PMID: 16627882.
Combination of systemic hypothermia and N-acetylcysteine attenuates hypoxic-ischemic brain injury in neonatal rats.
Europe PMC ID: 16627882
Chujor et al. 1991. Int J Lepr Other Mycobact Dis. 59(4):590-7. PMID: 1724981.
Serum antibodies against peripheral nervous system antigens in leprosy.
Europe PMC ID: 1724981
Brunner et al. 1989. J Neurochem. 52(1):296-304. PMID: 2462020.
Differential ultrastructural localization of myelin basic protein, myelin/oligodendroglial glycoprotein, and 2',3'-cyclic nucleotide 3'-phosphodiesterase in the CNS of adult rats.
Europe PMC ID: 2462020
Groome et al. 1986. J Neuroimmunol. 12(4):253-64. PMID: 2428830.
Region-specific immunoassays for human myelin basic protein.
Europe PMC ID: 2428830
Groome et al. 1985. Neurochem Int. 7(2):309-17. PMID: 20492929.
Preparation and properties of monoclonal antibodies to myelin basic protein and its peptides.
Europe PMC ID: 20492929
Add a reference
References: 12 entries
Marignier et al. 2010. Brain. 133(9):2578-91. PMID: 20688809.
Oligodendrocytes are damaged by neuromyelitis optica immunoglobulin G via astrocyte injury.
Jatana et al. 2006. Pediatr Res. 59(5):684-9. PMID: 16627882.
Combination of systemic hypothermia and N-acetylcysteine attenuates hypoxic-ischemic brain injury in neonatal rats.
Chujor et al. 1991. Int J Lepr Other Mycobact Dis. 59(4):590-7. PMID: 1724981.
Serum antibodies against peripheral nervous system antigens in leprosy.
Brunner et al. 1989. J Neurochem. 52(1):296-304. PMID: 2462020.
Differential ultrastructural localization of myelin basic protein, myelin/oligodendroglial glycoprotein, and 2',3'-cyclic nucleotide 3'-phosphodiesterase in the CNS of adult rats.
Groome et al. 1986. J Neuroimmunol. 12(4):253-64. PMID: 2428830.
Region-specific immunoassays for human myelin basic protein.
Groome et al. 1985. Neurochem Int. 7(2):309-17. PMID: 20492929.
Preparation and properties of monoclonal antibodies to myelin basic protein and its peptides.
Add a reference