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Anti-Vitronectin V65 subunit, Polyclonal [pAb-V65]

Invented at University Of Bristol

Info

Catalogue Number 153621
Applications ELISA WB
Antigen/Gene or Protein Targets Vitronectin V65 subunit
Synonyms Complement S Protein antibody, Epibolin antibody, S Protein antibody, Serum Spreading Factor antibody, Somatomedin B antibody, Vitronectin V65 subunit antibody, VN antibody, VNT antibody, VTNC_HUMAN antibody
Reactivity Human
Relevance Osteoarthritis (OA) is the most common chronic joint disease usually diagnosed at relatively advanced stages when there is irreparable damage to the joint(s). Recently, two novel biomarkers C3f and V65 were identified which appear to be OA-specific and therefore potential markers of early disease. The polyclonal antibody Anti-Vitronectin V65 subunit [pAb-V65] was developed and validated for the measurement of V65 in patient serum.
Host Rabbit
Immunogen V65 peptide-carrier conjugate. The carrier protein is Keyhole Limpet Haemocyanin (KLH).
Concentration 1 mg/mL
Formulation PBS
Method of Purification Serum was first purified using Protein G and then a second affinity purification step was performed using the peptide antigen coupled to sepharose.
Positive Control Synthetic peptide
Research Area Cardiovascular, Immunology

References

There are 2 reference entries for this reagent.

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References: 2 entries

Ourradi et al. 2017. PLoS One. 12(7):e0181334. PMID: 28715494.

ELISA WB

Development and validation of novel biomarker assays for osteoarthritis.

Europe PMC ID: 28715494


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References: 2 entries

Ourradi et al. 2017. PLoS One. 12(7):e0181334. PMID: 28715494.

ELISA WB

Development and validation of novel biomarker assays for osteoarthritis.


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