Anti-HuR [4C8] (ChIP Grade)
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Info
| Catalogue Number | 153520 |
| Applications | ChIP ELISA IHC EMSA |
| Antigen/Gene or Protein Targets | HuR |
| Synonyms | ELAV-like protein 1, Human antigen R |
| Reactivity | Human |
| Relevance |
ELAV-like protein 1 or HuR (human antigen R) is a protein that in humans is encoded by the ELAVL1 gene. The protein encoded by this gene is a member of the ELAVL protein family. This encoded protein contains 3 RNA-binding domains and binds cis-acting AU-rich elements. It stabilizes mRNAs and thereby regulates gene expression. A popular technique is to use anti-HuR antibodies to pull out interacting mRNAs and thereby analyse gene expression in a particular tissue. Monoclonal antibody 4C8 was selected by its ability to bind to the HuR/mRNA complex and thus is very useful for EMSA, ChIP and CLIP studies. |
| Host | Mouse |
| Immunogen | HuR peptide |
| Subclass | IgG1 |
| Research Area | Gene Expression |
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