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Anti-CD119 [11F4]
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Info

Catalogue Number 153510
Applications ELISA IHC WB
Antigen/Gene or Protein Targets CD119
Synonyms Interferon gamma receptor 1, IFN gamma receptor 1
Reactivity Mouse
Relevance The monoclonal antibody 11F4 recognizes mouse CD119 also known as IFN gamma receptor 1. CD119 heterodimerizes with IFN gamma receptor 2 (AF-1) forming the Class II cytokine receptor. The ligand IFN gamma binds IFN gamma receptor 1 subunit but signal transduction transpires via the IFN gamma receptor 2 subunit. The receptor is involved in host defense, expression is broad including B cells, NK cells, macrophages and dendritic cells as well as other non-hematopoietic cell types.
Host Mouse
Immunogen CD119
Subclass IgG1
Notes Purified using protein G
Research Area Cell Type or Organelle Marker, Cell Signaling & Signal Transduction, Immunology

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