Anti-HuD [15A9] (ChIP Grade)
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Info
| Catalogue Number | 153502 |
| Applications | ChIP ELISA IHC IP WB |
| Antigen/Gene or Protein Targets | HuD |
| Synonyms | ELAV-like protein 4 |
| Reactivity | Human |
| Relevance |
HuD otherwise known as ELAV-like protein 4 is a protein that in humans is encoded by the ELAVL4 gene. The HuD/ELAVL4 protein is an RNA-binding protein. HuD is expressed only in neurons and it binds to AU-rich element-containing mRNAs. As a result of this interaction the half-life of the transcript is increased. HuD is important in neurons during brain development and plasticity. Monoclonal 15A9 was generated against a unique HuD peptide and does not react with HuR, HuC, or Hel-N1. Monoclonal 15A9 works well in western blot, IHC and provides an excellent marker for neuronal cells. However, it was specifically selected becasue of its abiity to supershift HuD/mRNA ribonucleoprotein complexes. Thus, it is the ideal reagent for CHIP or RIP studies to specifically identify novel HuD targets in neuronal cells. |
| Host | Mouse |
| Subclass | IgG2b |
| Research Area | Developmental Biology, Gene Expression, Neurobiology |
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