Anti-HA (H1N1) [LM41] monoclonal antibody
Invented by Nigel Dimmock
Invented at University Of Warwick
- Datasheet
- References (1)
- Inventor Info
Info
| Catalogue Number | 153417 |
| Applications | ELISA Fn |
| Antigen/Gene or Protein Targets | A/WSN (H1N1) hemagglutinin |
| Synonyms | Hemagglutinin Antibody, Anti-HA, HA, Antibody, Anti-Influenza A, Anti-H1N1 HA, Influenza A Antibody, Flu Antibody, AWSN Antibody, H1N1 Antibody, Anti-AWSN, A/WSN Antibody, Anti-A/WSN |
| Reactivity | Virus |
| Relevance | The hemagglutinin (HA) protein is one of two major surface glycoproteins on the envelope of influenza A virus. The HA protein is responsible for receptor binding to host cells and for viral entry and is therefore the primary target of neutralizing antibodies. LM41 recognises an epitope of the A/WSN (H1N1) HA antigen only when expressed in H-2k cells. LM41 inhibited Ag-specific, MHC class I-restricted lysis of H-2k target cells infected with a vaccinia recombinant virus expressing the HA of A/WSN by CTL from A/WSN virus-infected H-2k mice. |
| Host | Mouse |
| Immunogen | C3WHe-mg (H-2k) mice were infected with A/WSN (H1N1) |
| Subclass | IgM |
| Myeloma Used | Sp2/0-Ag14 |
| Research Area | Immunology, Virology |
References: 1 entry
References: 1 entry
Inventor Information
Inventors
|
Nigel Dimmock |
