Anti-Ribophorin-1 [CEL5C]
Invented by Prof Birgit Lane from A*STAR Accelerate Technologies Pte Ltd
Invented at University of Dundee
- Datasheet
- References (2)
- Inventor Info
Info
| Catalogue Number | 153410 |
| Applications | IP WB |
| Antigen/Gene or Protein Targets | ribophorin type 1 |
| Synonyms | OST1; RBPH1 |
| Reactivity | Xenopus laevis |
| Relevance | Ribophorin I is an essential subunit of oligosaccharyltransferase (OST), which is also known as dolichyl-diphosphooligosaccharide--protein glycosyltransferase. OST catalyses the transfer of an oligosaccharide from dolichol pyrophosphate to selected asparagine residues of nascent polypeptides as they are translocated into the lumen of the rough endoplasmic reticulum. Ribophorin I and OST48 are thought to be responsible for OST catalytic activity. Both yeast and mammalian proteins are glycosylated but the sites are not conserved. Glycosylation may contribute towards general solubility but is unlikely to be involved in a specific biochemical function. Most family members are predicted to have a transmembrane helix at the C terminus of this region. |
| Host | Mouse |
| Immunogen | Nuclei formed in vitro in Xenopus egg extract |
| Subclass | IgG1 |
| Molecular Weight (kDa) | 65 |
| Research Area | Cell Signaling & Signal Transduction |
References: 2 entries
Addinall et al. 2001. J Biol Chem. 276(19):15939-44. PMID: 11278950.
Phosphorylation by cdc2-CyclinB1 kinase releases cytoplasmic dynein from membranes.
Europe PMC ID: 11278950
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References: 2 entries
Addinall et al. 2001. J Biol Chem. 276(19):15939-44. PMID: 11278950.
Phosphorylation by cdc2-CyclinB1 kinase releases cytoplasmic dynein from membranes.
Add a reference
