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Anti-CEACAM1 [F7]

Invented by Dr Bernhard B. Singer at LeukoCom

Info

Catalogue Number 153379
Applications ELISA FACS IHC IP WB
Antigen/Gene or Protein Targets CEACAM1
Synonyms CD66, BGP 1, BGP, CD66a, Carcinoembryonic Antigen Related Cell Adhesion Molecule 1; CD66a Antigen; BGP1; BGP; Biliary Glycoprotein 1; Antigen CD66
Reactivity Rat
Relevance Carcinoembryonic antigen related cell adhesion molecules (CEACAM) (CD66a) belong to the immunoglobulin superfamily. They are highly glycosylated proteins with the typical N-terminal variable Ig-like domain followed by 0-6 constant Ig-like domains. A hydrophobic transmembrane domain with a cytoplasmic tail anchors CEACAM1 to the cell membrane. CEACAM1 is known as an epithelial tumour suppressor and an angiogenic growth factor.
Host Mouse
Subclass IgG1 kappa
Positive Control lysate from rat bladder cell line endogenously expressing ratCEACAM1
Notes Does not cross-react with human CEACAM-1, -3. -4, -5, -6, 7 and -8, mouse CEACAM1 and mouse CEACAM2.
Binds specific to the N-domain of rat CEACAM1
Research Area Adhesion, Cancer, Cell Type or Organelle Marker

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