Anti-CD29, Recombinant [12G10]
Invented at University of Manchester
- Datasheet
- References (1)
- Inventor Info
Info
| Catalogue Number | 153365 |
| Applications | ELISA FACS IHC IF IP WB |
| Antigen/Gene or Protein Targets | CD29 (Integrin b1 chain) |
| Synonyms | Integrin Subunit Beta 1; Glycoprotein Iia; MSK12; GPIIA; FNRB; MDF2; Very Late Activation Protein; Beta Polypeptide; Fibronectin Receptor Subunit Beta; Integrin VLA-4 Beta Subunit; CD29 Antigen; VLA-BETA; CD29; VLAB |
| Reactivity | Human |
| Relevance | CD29 is a member of the family of integrins, membrane receptors involved in cell adhesion and recognition in a variety of processes including embryogenesis, hemostasis, tissue repair, immune response and metastatic diffusion of tumor cells. |
| Host | Mouse |
| Immunogen | Purified human β1 integrin preparation from HT1080 fibrosarcoma cell extract. |
| Subclass | IgG1 |
| Formulation | PBS |
| Concentration | 1mg/ml |
| Research Area | Adhesion, Cancer, Cell Signaling & Signal Transduction, Epigenetics & Nuclear Signalling, Gene Expression, Immunology |
| Notes |
12G10 has been shown to recognize a ligand-induced binding site of human β1 integrin. The binding is increased in the presence of a fibronectin ligand. This antibody also enhances alpha 5 – beta 1 fibronectin interactions. Recombinant monoclonal antibody produced from the original monoclonal. Manufactured using Absolute Antibody’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma. |
References: 1 entry
Original hybridoma first published in: Mould et al. 1995. FEBS Lett. 363(1-2):118-22. PMID: 7537221.
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References: 1 entry
Original hybridoma first published in: Mould et al. 1995. FEBS Lett. 363(1-2):118-22. PMID: 7537221.
Add a reference
