Anti-CD72, Recombinant [BU40]
Invented at University Of Birmingham
- Datasheet
- References (1)
- Inventor Info
Info
| Catalogue Number | 153264 |
| Applications | FACS IHC IP WB |
| Antigen/Gene or Protein Targets | CD72 |
| Synonyms | CD72 Molecule; CD72 Antigen; Lyb-2; CD72b; LYB2 |
| Reactivity | Human |
| Relevance | CD72, a member of the C-type lectin superfamily, is a 45 kDa type II transmembrane glycoprotein. It is expressed from the pro-B through to the mature B cell stage but absent in terminally differntiated plasma cells. Ligation of CD72 enhances B cell growth and proliferation. |
| Host | Mouse |
| Immunogen | HF B1 plasmacytoid cell line. Considered to be “late B like”. |
| Subclass | IgG2a |
| Formulation | PBS |
| Concentration | 1mgml-1 |
| Research Area | Immunology |
| Notes |
Recombinant monoclonal antibody produced from the original monoclonal cell line. Manufactured using Absolute Antibody’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma. Six products based on this clone: - Anti-CD72 [BU40], Mouse IgG2a, Kappa - Anti-CD72 [BU40], Mouse IgG2a, Kappa, engineered Fc domain containing key point mutations that abrogate binding to Fc gamma receptors - Anti-CD72 [BU40], Rabbit IgG, Kappa - Anti-CD72 [BU40], Human IgG4-S228P, Kappa - Anti-CD72 [BU40], Human IgG1, Kappa - Anti-CD72 [BU40], Human IgG1, Kappa, engineered Fc domain containing key point mutations that abrogate binding to Fc gamma receptors |
References: 1 entry
Original hybridoma first published in: Van de Velde et al. 1991. Nature. 351(6328):662-5. PMID: 1711157.
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References: 1 entry
Original hybridoma first published in: Van de Velde et al. 1991. Nature. 351(6328):662-5. PMID: 1711157.
Add a reference
