Anti-Germinal Centre macrophages [BU83]
Invented by Dr Margaret Goodall from University Of Birmingham
Invented at University Of Birmingham
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Info
| Catalogue Number | 153227 |
| Applications | IHC |
| Antigen/Gene or Protein Targets | Macrophages |
| Synonyms | PB33 |
| Reactivity | Human |
| Relevance | Macrophages are a type of white blood cell which through a process called phagocytosis engulfs and digests cellular debris, foreign substances, microbes, cancer cells. They can be found in all tissues where they play a critical role in the innate immune system and also help initiate adaptive immunity through recruiting lymphocytes and other immune cells. Germinal centres are sites within secondary lymph nodes where mature B lymphocytes proliferate, differentiate and mutate their antibody genes, enabling switching of their class of antibody during the course of infection. |
| Host | Mouse |
| Immunogen | Pre-B cells |
| Subclass | IgG2a |
| Strain | Balb/c |
| Research Area | Immunology |
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