Anti-S100A9, Polyclonal [NH3]
Invented by Prof Nancy Hogg from Cancer Research UK London Research Institute: Lincoln's Inn Fields
Invented at Cancer Research UK London Research Institute: Lincoln's Inn Fields
- Datasheet
- References (4)
- Inventor Info
Info
| Catalogue Number | 153162 |
| Applications | IHC WB |
| Antigen/Gene or Protein Targets | S100A9 |
| Synonyms | MRP-14, calgranulin B |
| Reactivity | Human |
| Relevance | S100A9, together with heterodimeric partner S100A8, is a major biomarker of inflammation both in released form in serum and through increased expression in epithelial tissue and in many tumours. |
| Host | Rabbit |
| Immunogen | Recombinant human S100-A9 (MRP-14) |
| Formulation | Whole serum |
| Molecular Weight (kDa) | 14 |
| Notes |
Western blotting 1:50,000; immunohistology 1;5000 Application dilutions are based on using crude serum. Staining pattern (sub-cellular localisation of antibody): cytosolic protein (with partner S100A8 constitutes 45% protein in neutrophils; 1% in monocytes; also secretory epithelium). |
| Positive Control | Human neutrophils |
| Research Area | Cancer, Cell Signaling & Signal Transduction, Immunology |
References: 4 entries
Robinson et al. 2002. J Biol Chem. 277(5):3658-65. PMID: 11723110.
The S100 family heterodimer, MRP-8/14, binds with high affinity to heparin and heparan sulfate glycosaminoglycans on endothelial cells.
Europe PMC ID: 11723110
Robinson et al. 2000. Biochem Biophys Res Commun. 275(3):865-70. PMID: 10973813.
A comparison of human S100A12 with MRP-14 (S100A9).
Europe PMC ID: 10973813
Add a reference
References: 4 entries
Robinson et al. 2002. J Biol Chem. 277(5):3658-65. PMID: 11723110.
The S100 family heterodimer, MRP-8/14, binds with high affinity to heparin and heparan sulfate glycosaminoglycans on endothelial cells.
Robinson et al. 2000. Biochem Biophys Res Commun. 275(3):865-70. PMID: 10973813.
A comparison of human S100A12 with MRP-14 (S100A9).
Add a reference
