Anti-TFEC, Polyclonal [TFEC]
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Info
| Applications | ELISA IF WB |
| Antigen/Gene or Protein Targets | TFEC |
| Reactivity | Human and Mouse |
| Relevance | Transcriptional regulator that acts as a repressor or an activator. Acts as a transcriptional repressor on minimal promoter containing element F (that includes an Ebox sequence). Binds to element F in an Ebox sequencespecific manner. Acts as a transcriptional transactivator on the proximal promoter region of the tartrateresistant acid phosphatase (TRAP) Ebox containing promoter Collaborates with MITF in target gene activation Acts as a transcriptional repressor on minimal promoter containing mu E3 enhancer sequence. Binds to mu E3 DNA sequence of the immunoglobulin heavychain gene enhancer. Binds DNA in a homo or heterodimeric form. |
| Host | Rabbit |
| Immunogen | 3 synthetic peptides (human) conjugated to KLH |
| Formulation | 0.5 X PBS, containing a final concentration of 50% Glycerol, 0.1% BSA and 0.01% Thimerosal. |
| Method of Purification | Immunogen affinity purification |
| Molecular Weight (kDa) | 38.7 |
| Research Area | Epigenetics & Nuclear Signalling |
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