Anti-WASF2 [ZZ36-12]
Invented at IFOM-IEO
- Datasheet
- References (2)
- Inventor Info
Info
| Applications | IF IP WB |
| Antigen/Gene or Protein Targets | Wiskott Aldrich syndrome protein family member 2 |
| Synonyms | DICTYOSTELIUM, dJ393P12.2, IMD2, Protein WAVE-2, Putative Wiskott Aldrich syndrome protein family member 4, SCAR 2, SCAR, SCAR2, Suppressor of cyclic-AMP receptor (WASP family), Verprolin homology domain-containing protein 2, |
| Reactivity | Human and Mouse |
| Relevance | Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. |
| Host | Mouse |
| Subclass | IgG1 kappa |
| Myeloma Used | Sp2/0 |
| Research Area | Cancer, Cell Signaling & Signal Transduction |
References: 2 entries
Innocenti et al. 2004. Nat Cell Biol. 6(4):319-27. PMID: 15048123.
Abi1 is essential for the formation and activation of a WAVE2 signalling complex.
Europe PMC ID: 15048123
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References: 2 entries
Innocenti et al. 2004. Nat Cell Biol. 6(4):319-27. PMID: 15048123.
Abi1 is essential for the formation and activation of a WAVE2 signalling complex.
Add a reference
