Anti-BRCA2 [B22B6]
Invented at Icahn School Of Medicine At Mount Sinai
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Info
| Applications | WB |
| Antigen/Gene or Protein Targets | BRCA2 |
| Synonyms | BRCA 2, BRCA1/BRCA2 containing complex subunit 2, Brca2, BRCA2_HUMAN, BRCC 2, BRCC2, Breast and ovarian cancer susceptibility gene early onset, Breast cancer 2 early onset, Breast Cancer 2 tumor suppressor, Breast cancer susceptibility protein BRCA2, Breast cancer type 2 susceptibility protein, BROVCA2, FACD, FAD 1, FAD, FAD1, FANCB, FANCD 1 |
| Reactivity | Human |
| Relevance | Breast Cancer Type 2 susceptibility protein (BRCA2) is a tumour suppressor gene. BRCA2 is involved in the repair of chromosomal damage, specifically in localising Rad51 to double strand breaks. BRCA2 and BRCA1 are frequently mutated in cases of hereditary breast and ovarian cancer. |
| Host | Mouse |
| Subclass | IgG2b |
| Research Area | Cancer, DNA Damage and Repair, Epigenetics & Nuclear Signalling |
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