Anti-activated MMP1 [5C10]
Invented by Ayham Alnabulsi from Vertebrate Antibodies Limited
Invented at Vertebrate Antibodies Limited
- Datasheet
- References (0)
- Inventor Info
Info
![Western blotting was performed on matrix metalloproteinases (MMPs) 1, 2, 3 and 9 in both proenzyme and activated forms using anti-activated MMP1 [5C10] antibody. An approximately 40kDa protein was detected for activated MMP1.](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,q_auto/3b7afacf-d070-44bf-a425-cd28041f34fb.png)
![Western blotting was performed on matrix metalloproteinases (MMPs) 1, 2, 3 and 9 in both proenzyme and activated forms using anti-activated MMP1 [5C10] antibody. An approximately 40kDa protein was detected for activated MMP1.](https://res.cloudinary.com/ximbio/image/upload/c_limit,fl_lossy,h_282,q_auto,w_368/3b7afacf-d070-44bf-a425-cd28041f34fb.png)
![Image thumbnail for Anti-activated MMP1 [5C10]](https://res.cloudinary.com/ximbio/image/upload/c_fit,fl_lossy,h_45,q_auto/3b7afacf-d070-44bf-a425-cd28041f34fb.png)
| Catalogue Number | 152766 |
| Applications | WB |
| Antigen/Gene or Protein Targets | activated human matrix metalloproteinase 1 (MMP1) |
| Synonyms | actMMP-1, actMMP1, activated-MMP1, activated MMP1, activated-MMP-1, activated MMP-1, Fibroblast collagenase |
| Reactivity | Human |
| Relevance | Matrix metalloproteinases (MMPs) are synthesized as inactive zymogens with a pro-peptide domain that must be removed before the enzyme is active. MMP1 breaks down the interstitial collagens, types I, II, and III hence it is an important feature of development, morphogenesis, tissue repair and remodeling. The anti-activated MMP1 [clone 5C10] antibody specifically targets the active form of MMP1 and is suitable for western blot only; it does not cross-react with proenzyme MMP1, or proenzyme or active forms of MMP2, MMP3 and MMP9. |
| Host | Mouse |
| Immunogen | Ovalbumin-conjugated synthetic peptide; FVLTEGNPRC |
| Positive Control | Activated recombinant MMP-1 |
| Subclass | IgG1 kappa |
| Molecular Weight (kDa) | 40 |
| Myeloma Used | P3X63Ag8.653 |
| Strain | Balb/c |
| Research Area | Cancer, Cardiovascular, Cell Signaling & Signal Transduction |
References
There are 0 reference entries for this reagent.
References: 0 entry
There is no reference for this reagent yet, feel free to use the button below to suggest one.
Add a reference
References: 0 entry
There is no reference for this reagent yet, feel free to use the button below to suggest one.
Add a reference
