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SVCT Cell Line

Invented by Dr Sidney Chang from Retired Consultant
Invented at Marie Curie Research Institute

Info

Catalogue Number 152701
Host Human
Tissue Breast
Disease Keywords Breast cancer
Model Immortalised Line
Relevance SVCT has been established from human breast epithelial cells being transfected with SV40. The cell line shows an abnormal karyotype and was not tumourigenic in athymic male nude mice. SVCT have been found positive for the expression of keratin 7, 8 and 18 but negative for keratin 19. Epithelial cells, dome formation when confluent.
Conditional No
Research Area Cancer, Drug Discovery & Development
Growth/Phenotype Keywords Adherent
Recommended Growing Conditions DMEM + 2mM Glutamine + 5µg/ml Hydrocortisone + 10µg/ml Insulin + 10% Foetal Bovine Serum (FBS).
Cellosaurus ID CVCL_2718

References

There are 2 reference entries for this reagent.

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References: 2 entries

Chang et al. 1986. Biochim Biophys Acta. 823(3):161-94. PMID: 2423124.

In vitro transformation of human epithelial cells.

Europe PMC ID: 2423124


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References: 2 entries

Chang et al. 1986. Biochim Biophys Acta. 823(3):161-94. PMID: 2423124.

In vitro transformation of human epithelial cells.


Add a reference

Inventor Information