Cancer Research Technology
Log in Register
Menu

Anti-RAP-1 [2.29]

Info

Applications N/A
Antigen/Gene or Protein Targets RAP1
Reactivity Plasmodium
Relevance In considering methods for immunological control of Plasmodium falciparum malaria it is essential to know more about antigenic diversity within and between natural populations of the parasite from major endemic areas. A successful malaria vaccine would stimulate an individual's immune system to respond to the malaria parasite and prevent serious clinical disease. Many different groups are currently developing potential vaccines. Rhoptry associated protein 1 (RAP1) and 2 (RAP2), together with a poorly described third protein RAP3, form the low molecular weight complex within the rhoptries of Plasmodium falciparum. These proteins are thought to play a role in erythrocyte invasion by the extracellular merozoite and are important vaccine candidates.
Host Mouse
Immunogen Schizonts from the K1 isolate of P. falciparum
Subclass IgG1
Myeloma Used P3/NS1/1-Ag4.1
Strain Balb/c
Notes Recognises rhoptry-associated protein 1 (RAP1) of P. falciparum.
UK Biosafety level: 1
Research Area Cell Type or Organelle Marker, Epigenetics & Nuclear Signalling, Parasitology

References

There are 1 reference entries for this reagent.

View All References

References: 1 entry

Hall et al. 1983. Mol Biochem Parasitol. 7(3):247-65. PMID: 6350871.


Add a reference

References: 1 entry

Hall et al. 1983. Mol Biochem Parasitol. 7(3):247-65. PMID: 6350871.


Add a reference

Inventor Information

No inventors are currently linked to this reagent.

Add an inventor