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Anti-B2M [YTH470.5]

Invented by Herman Waldmann , Helen Tighe
Invented at University of Cambridge

Info

Applications FACS
Antigen/Gene or Protein Targets B2M
Reactivity Human
Relevance B2M is a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. The antimicrobial protein displays antibacterial activity in amniotic fluid. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia.
Research Area Cancer, Cardiovascular

References

There are 1 reference entries for this reagent.

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References: 1 entry

Bindon et al. 1988. Eur J Immunol. 18(10):1507-14. PMID: 2973413.


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References: 1 entry

Bindon et al. 1988. Eur J Immunol. 18(10):1507-14. PMID: 2973413.


Add a reference

Inventor Information

Inventors

Herman Waldmann

Herman Waldmann

Helen Tighe

Helen Tighe

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