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Info
Applications | IHC |
Antigen/Gene or Protein Targets | MELAN-A |
Reactivity | Human |
Relevance | MELAN-A was originally identified by functional screening of expression libraries using melanoma-reactive cytolytic T lymphocytes isolated from melanoma patients. Its expression is restricted to melanin-producing cells, including normal and transformed skin melanocytes and retinal pigment epithelium. Approximately 90% of primary and 80% of metastatic melanoma tumours express MELAN-A transcripts. |
Host | Mouse |
Subclass | IgG1 |
Research Area | Cancer, Cell Type or Organelle Marker |