Anti-TAF11 [15TA-2B4]
- Datasheet
- References (8)
- Inventor Info
Info
| Applications | ELISA IF IP WB |
| Antigen/Gene or Protein Targets | TAF11 |
| Reactivity | Human and Mouse |
| Relevance | Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. TAF11 is a small subunit of TFIID that is present in all TFIID complexes and interacts with TBP. |
| Host | Mouse |
| Immunogen | Recombinant human TAF11 protein: epitope localized between aa 71 and 86 |
| Subclass | IgG1 kappa |
| Notes |
Available in 100ul units as ascites. Recommended dilutions: 1/500 - 1/5000 |
| Research Area | Epigenetics & Nuclear Signalling |
References: 8 entries
Mengus et al. 2000. J Biol Chem. 275(14):10064-71. PMID: 10744685.
The human transcription factor IID subunit human TATA-binding protein-associated factor 28 interacts in a ligand-reversible manner with the vitamin D(3) and thyroid hormone receptors.
Europe PMC ID: 10744685
Birck et al. 1998. Cell. 94(2):239-49. PMID: 9695952.
Human TAF(II)28 and TAF(II)18 interact through a histone fold encoded by atypical evolutionary conserved motifs also found in the SPT3 family.
Europe PMC ID: 9695952
May et al. 1996. EMBO J. 15(12):3093-104. PMID: 8670810.
Human TAF(II28) promotes transcriptional stimulation by activation function 2 of the retinoid X receptors.
Europe PMC ID: 8670810
Mengus et al. 1995. EMBO J. 14(7):1520-31. PMID: 7729427.
Cloning and characterization of hTAFII18, hTAFII20 and hTAFII28: three subunits of the human transcription factor TFIID.
Europe PMC ID: 7729427
Add a reference
References: 8 entries
Mengus et al. 2000. J Biol Chem. 275(14):10064-71. PMID: 10744685.
The human transcription factor IID subunit human TATA-binding protein-associated factor 28 interacts in a ligand-reversible manner with the vitamin D(3) and thyroid hormone receptors.
Birck et al. 1998. Cell. 94(2):239-49. PMID: 9695952.
Human TAF(II)28 and TAF(II)18 interact through a histone fold encoded by atypical evolutionary conserved motifs also found in the SPT3 family.
May et al. 1996. EMBO J. 15(12):3093-104. PMID: 8670810.
Human TAF(II28) promotes transcriptional stimulation by activation function 2 of the retinoid X receptors.
Mengus et al. 1995. EMBO J. 14(7):1520-31. PMID: 7729427.
Cloning and characterization of hTAFII18, hTAFII20 and hTAFII28: three subunits of the human transcription factor TFIID.
Add a reference
